Levofloxacin hydrochloride is suitable for genitourinary infections caused by sensitive bacteria, including simple and complicated urinary tract infections, bacterial prostatitis, Neisseria gonorrhoeae urethritis or cervicitis (including those caused by enzyme production). Respiratory infections, including acute bronchial infections caused by sensitive Gram-negative bacilli and pulmonary infections. Gastrointestinal infection, caused by Shigella, Salmonella, enterotoxin-producing Escherichia coli, Aeromonas hydrophila, Vibrio parahaemolyticus. It can also treat systemic infections such as typhoid, bone and joint infections, skin and soft tissue infections and sepsis.
It is the left-handed body of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hinder bacterial DNA replication.
Wide antibacterial spectrum and strong antibacterial effect. For most Enterobacteriaceae bacteria, such as Escherichia coli, Klebsiella, Serratia, Proteus, Shigella, Salmonella, Citrobacter, Acinetobacter, and patina Gram-negative bacteria such as monocytogenes, Haemophilus influenzae, and Neisseria gonorrhoeae have strong antibacterial activity. It also has good antibacterial activity against some methicillin-sensitive Staphylococcus, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus mutans and other Gram-positive bacteria, Legionella, Mycoplasma and Chlamydia, but it has effects on anaerobic bacteria and Enterococcus. Poor.
This product is suitable for the following mild to moderate infections caused by sensitive bacteria;
Respiratory infections: acute bronchitis, acute exacerbation of chronic bronchitis, diffuse bronchiolitis, bronchiectasis complicated with infection, pneumonia, tonsillitis (abscess around the tonsils);
Urinary tract infections: pyelonephritis, complicated urinary tract infections, etc.;
Reproductive system infections: acute prostatitis, acute epididymitis, intrauterine infection, uterine annexitis, pelvic inflammatory disease (can be combined with metronidazole when suspected of anaerobic infection);
Skin and soft tissue infections: infectious impetigo, cellulitis, lymphatic (knot) inflammation, subcutaneous abscess, perianal abscess, etc.;
Intestinal infections: bacterial dysentery, infectious enteritis, Salmonella enteritis, typhoid fever and paratyphoid fever;
Various infections in patients with sepsis, neutropenia, and immunocompromised patients;
Other infections: mastitis, trauma, burns and post-operative wound infections, abdominal infections (with metronidazole if necessary), cholecystitis, cholangitis, bone and joint infections, and ENT infections.